Mayo Clinic Pharmacy Grand Rounds

The tXa Files: Bleeding Management with Tranexamic Acid

Nicholas Vollmer, Pharm.D. (@VollmerNick) discusses pharmacological characteristics of tranexamic acid, compares and contrasts primary literature for proposed tranexamic acid indications and identifies pharmacotherapy pearls related to tranexamic acid.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Anaphylaxis Attacks: Nutting to Worry About?

Jamie Reed, Pharm.D., BCPS, recalls the pathophysiology of anaphylaxis, differentiates pharmacological options for prevention of anaphylaxis and determines effective acute pharmacological and non-pharmacological management of anaphylaxis.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Cystinuria: Treatment and Management Options

Sarah Stieven, Pharm.D. reviews the pathophysiology of cystinuria, describes non-pharmacologic and pharmacologic treatment options for cystinuria and reviews potential side effects of pharmacologic options of cystinuria and how to manage

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Direct Oral Anticoagulants in the Obese Population: Does One Size Fit All?

Joseph Zieminski, Pharm.D. observed in the obese population, discusses pharmacokinetic changes and outcomes data of direct oral anticoagulants (DOACs) in obese patients and selects an appropriate DOAC for use in an obese patient case.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

GABbing About Pain: Perioperative Use of Gabapentinoids for Acute Pain Management

Joseph Osborne II, Pharm.D. (@JOzempic) describes the pharmacology of the gabapentinoids, reviews literature pertaining to perioperative gabapentinoid use for acute pain management and identifies toxicity, misuse, and abuse considerations relating to gabapentinoid use. 

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Probiotics or No-biotics: Pros and Cons of Probiotic Use

Jennifer Adema, Pharm.D., M.B.A. (@JAdemaPharmD) identifies different strains of bacteria found in probiotics, discusses target populations for probiotic use and describes the use of probiotics in immunocompromised patients. 

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Don’t be Salty: Non-inotropic Strategies to Overcome Loop Diuretic Resistance in Acute Decompensated Heart Failure

Lindsay Moreland-Head, Pharm.D. (@morelandln) describes the pathophysiology of intravascular versus tissue congestion in Acute Decompensated Heart Failure (ADHF), explains the mechanisms of diuretic resistance in ADHF and why non-inotropic strategies may help augment diuresis and discusses the literature on non-inotropic strategies to decongest patients and overcome loop diuretic resistance in ADHF.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Sickle Me Pink: Promising Advances in Sickle Cell Disease Management

Deann Tims, Pharm.D. will describe the pathiophysiology and complications associate with sickle cell disease, review standard treatment modalities of sickle cell disease and discuss recent literature regarding advancements in sickle cell disease therapy.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

TramaDO or TramaDON’T? Re-Evaluating the Role of Tramadol in Pain Management

Kellyn K. Engstrom, Pharm.D., (@KellynEPHarmD) discusses evidence for efficacy of tramadol for indications of acute or chronic pain in adults, describes major safety and pharmacokinetic considerations for the utilization of tramadol and assesses the current misuse and abuse potential of tramadol.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Protesting the Penicillin Allergy: The Power of De-Labeling

Nicholas J. Vollmer, Pharm.D., (@VollmerNick) describes the background of penicillin allergies, discusses consequences associated with mislabeled penicillin allergies and identifies strategies institutions can employ to combat the mislabeled penicillin allergies.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.