Mayo Clinic Pharmacy Grand Rounds

Emerging Antibiotics – Tetra(cycle)ine Back to Basics

Ashton C. Praska, PharmD (Twitter @ashpraka) describes tetracycline resistance mechanisms utilized by bacteria, identifies how Omadacycline/Eravacycline can overcome common tetracycline resistance mechanisms and identifies clinical scenarios where Omadacycline/Eravacycline could be considered for use.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Pharmacotherapy for the Treatment of Obesity

Kristina M. Thurber, PharmD, BCPS recognizes pharmacotherapy for the treatment of obesity and explain mechanisms of action for each class, discusses and compares clinical data and weight loss outcomes for common treatment options, and determines an optimal pharmacologic regimen for the treatment of obesity given patient-specific factors.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Off the Chain: The Drug Supply Chain and Medication Shortages

Jo Ann Leal, PharmD (Twitter @JoJoPharmD) describes the key components of the drug supply chain and the impact of drug shortages, identifies common organizational strategies used to mitigate drug shortages and evaluates recent national efforts to stabilize the drug supply chain.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Clostridioides difficile Infection: Do We C the Diff-erence in Preventing Recurrence?

Andrew (Andy) F. Wiener, PharmD (Twtitter @andywiener) describes the pathogenesis and risk factors of C. diff infection and recurrence, reviews the preferred treatment modalities for prevention of C. diff recurrence and describes the cost-benefit analysis supporting guideline-directed management of C. diff infections.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Pharmacologic Treatment of Drug Resistant Hypercholesterolemia

Seth M. Kriha, PharmD identifies guideline recommended treatment to reduce LDL-C, evaluates landmark clinical trials for novel therapeutic agents indicated for treatment resistant hypercholesterolemia and develops a pharmacologic care plan for a patient with treatment resistant hypercholesterolemia.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

It’s Going Tibia Okay: Supportive Bone Health in Oncology

Christopher R. Cahoon, PharmD defines the importance of optimizing bone health in patients with bone metastases and lytic lesions, describes preferred bone-targeted therapy for patients with malignancy-associated bone disease and discusses the safety limitations associated with bisphosphonates and RANKL inhibitors.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Preserving the Future: Fertility Preservation in Cancer Patients

Shienna A. Braga, PharmD explains the effects of select chemotherapeutic agents on gonadal function and fertility in cancer patients, recognizes the different modalities utilized for fertility preservation in adults and children with cancer and reviews current literature that describes the role of gonadotropin-releasing hormone agonists (GnRHa) in women diagnosed with cancer.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

SUPPosed SUPPort: Targeted Review of Supplements Recommended in Clinical Practice

Linda Huang, Pharm.D identifies considerations for use of select provider-recommended supplements, describes literature that helps explain use of select supplements in outpatient treatment plans and discusses patient cases that highlight place in therapy for supplement use.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Bridging the Gap: Controversies in Perioperative Anticoagulation Management

Ming May Zhang, PharmD (Twitter: @amayzhanggg) reviews key bleeding and thromboembolic risks that should be considered in the perioperative setting, describes the current evidence for perioperative warfarin management in atrial fibrillation, venous thromboembolism, and mechanical heart valves and discusses patient- and disease-specific risk factors that may impact decisions regarding perioperative bridging.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

To Measure or Not to Measure? Prophylactic Enoxaparin Management in Trauma Patients

Hailey A. Thompson, PharmD identifies the physiologic factors that increase venous thromboembolism risk in trauma patients, outlines current recommendations and their pitfalls for venous thromboembolism prophylaxis in trauma patients and discusses evidence for anti-Xa monitoring for venous thromboembolism prophylaxis with enoxaparin.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.