Mayo Clinic Pharmacy Grand Rounds

Put on Your Thinking CAP: Steroid Use in Community-Acquired Pneumonia?

Caitlin C. Schanz, PharmD (@Schanz_Caitlin) explains the pharmacological mechanism of steroid use in community-acquired pneumonia treatment, interprets literature assessing use of steroids in management of community-acquired pneumonia and relates efficacy and safety outcomes of steroids in community-acquired pneumonia to a patient case.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

When the CAR-T’s Over: Managing the Long-Term Complications of CAR-T Therapy

Alejandro Del Rio Verduzco, PharmD (Twitter: @Alejandro_DRV) defines the different short-term and long-term toxicities of CAR-T therapy, describes evidence for existing management strategies for late-term CAR-T toxicities and identifies evidence and reports of emerging late-term CAR-T toxicities.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

“Seeing R.E.D” Racial and Ethnic Disparities in Cardiovascular Disease State Medication

Aleesha Jantzen, PharmD describes social determinants of health that impact management of cardiovascular disease states, recognizes racial/ethnic disparities in management of atrial fibrillation, myocardial infection, hypertension, and heart failure and identifies pharmacist interventions to minimize racial/ethnic disparities in cardiovascular disease state management.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Nobody Likes Rejection: Therapeutic Drug Monitoring of Mycophenolate in Solid Organ Transplant

Tanner A. Melton, PharmD (Twitter @TAMeltonRx) reviews factors associated with inter- and intra-patient mycophenolate pharmacokinetic variability, describes current strategies to perform mycophenolate therapeutic drug monitoring and determines an optimal monitoring plan for the treatment of a solid organ transplant recipient.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Ascorbic Acid Episode IV: The Rise and Fall of Vitamin C

Mark P. Layden, PharmD, MBA (Twitter @Layden_Rx) describes the pathophysiology of sepsis and role of Vitamin C in the critically ill population, identifies the proposed benefits of Vitamin C use in the critically ill patient population and discusses updated literature on the current role of Vitamin C in sepsis.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Turning the Page on the Monoamine Story: Utilizing the NMDA Pathway for Major Depressive Disorder

Natalie T. Hagy, PharmD describes the monoamine and glutaminergic pathway for the treatment of major depressive disorder, recognizes response and remission rates of first line treatment for major depressive disorder and describes the clinical trials for dextromethorphan-bupropion and its impact on the landscape of major depressive disorder.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Pump It Up: An Overview of Diabetic Insulin Pumps

Lauren R. Stonerock, PharmD (@LStonerockRx) reviews the history of insulin delivery technology and its impact on diabetes management, identifies patient-specific factors associated with successful insulin pump use and discusses current insulin pumps and highlight their specific features.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

“Rheum” for Improvement: Review of Rheumatoid Arthritis Treatment Guidelines

Chelsea M. Morken, PharmD (@ChelseaMorken) explains the pathophysiology of rheumatoid arthritis (RA), describes the literature regarding cardiovascular risks with Janus-kinase inhibitors and recognizes appropriate initial therapy based on patient specific factors.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Don’t You Know that You’re Toxic? Cardiotoxicity Prevention and Treatment in Oncology

Uzoamaka (Uzo) C. Abajue, PharmD (@Uzo_Chi) discusses the manifestations, diagnosis, and classification of chemotherapy induced cardiotoxicity, identifies causative oncologic agents responsible for cardiotoxicities and outlines strategies for cardiotoxicity management due to oncologic agents.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Mab Scientists: Therapeutic Drug Monitoring with Eculizumab

Megan A. Galle, PharmD (@meganciclovir) reviews eculizumab’s mechanism of action and its role in treating antibody mediated rejection following solid organ transplantation, discusses laboratory testing methods available for eculizumab therapeutic drug monitoring and describes the role of therapeutic drug monitoring in eculizumab treatment optimization.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.